Ankylosing spondylitis is arthritis that majorly affects the spine.
It comes under a group of diseases called seronegative spondyloarthropathies. These cause inflammation in joints and spine.
Ankylosing spondylitis causes inflammation of the sacroiliac joint where the spine joins the pelvis or hip bone. The bones of the spine may grow and fuse together leading to a stiff spine and stooped over posture.
Symptoms include constant pain and stiffness in low back, fusion of spine that may spread to hips, neck, backs or ribs and pain and inflammation in ligaments and tendons. Chronic pain can lead to fatigue, fever and loss of appetite.
Ankylosing spondylitis may affect other joints such as hip, knee, shoulder and feet. It can affect other organs such as eyes, intestine, heart and lungs.
Causative factors of ankylosing spondylitis are unknown but individuals with gene HLA-B27 tend to develop ankylosing spondylitis.
Ankylosing spondylitis typically begins in adolescents and young adults, but affects people for the rest of their lives. Men are more likely to develop ankylosing spondylitis than are women.
Treatment is generally focussed on reducing pain and stiffness. Medications prescribed include:
- Non steroidal anti-inflammatory drugs: Such as ibuprofen and diclofenac to reduce pain and inflammation
- Opiod painkillers: To reduce pain
- Disease modifying anti-rheumatic drugs: To treat arthritis of spine
- Tumor necrosis factor alpha blockers and Anti-Interleukin 6 inhibitors: to inhibit and reduce production of inflammatory chemicals
Physical therapy and healthy diet also benefit in ankylosing spondylitis. In rare cases, surgery is recommended.
How can turmeric help in ankylosing spondylitis?
Turmeric is a potent anti-inflammatory and analgesic agent and these properties can benefit in treatment of ankylosing spondylitis.
1.It is an anti-inflammatory agent
Ankylosing spondylitis is characterised by inflammation in the lower end of the spine. Curcumin mediates its anti-inflammatory effect by :